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Sugar & Fat Cells
Sugar causes stem cells in becoming fat cells (Step One), instead of bone cells or cartilage cells. Sugar then causes the mature fat cell to get insulin resistant (Step Two this results in a further rise in bloodstream glucose and insulin resistance elsewhere in your body) and results in sugar to produce proinflammatory factors that harm other organs (Step Three).
Cramer C. et al. Stem Cell and Development 2010: Within this study, the scientists required stromal stem cells and treated all of them with growing concentrations of glucose. They observed that, because they added more glucose, less stem cells grew to become osteoblasts (A) and chondrocytes (B) and much more stem cells grew to become adipocytes (C). There have been several more nuances towards the study which are less essential for your audience. I’ve outlined the important thing data bars in red. They are stem cells produced from non-diabetic people. https://world wide web.ncbi.nlm.nih.gov/pubmed/20380516
Made up of 3 primary chemical ingredients: phenylalanine, aspartic acidity, and methanol
Nature, 2014 https://world wide web.ncbi.nlm.nih.gov/pubmed/25231862 – Nick
This paper shows that certain sugar substitutes screw up the gut microbial ecosystem, causing glucose intolerance and paving the way in which for metabolic disease.
They behind this paper started by analyzing what went down to various categories of rodents given any one of three different sugar substitutes (saccharin, sucralose, and aspartame) when compared with rodents given normal sugars (glucose and sucrose). Worryingly, all the rodents which were given the substitute sweeteners rapidly developed glucose intolerance, a harbinger of diabetes, weight problems, and metabolic disease.
They also noted the sugar substitutes altered the mice’s gut bacteria. To check to find out if the modification within the gut bacteria caused the substitute sweetener-caused metabolic disruption, they transplanted the gut bacteria in the rodents given sugar substitutes to rodents which had no gut bacteria. Affirmed, the recipient rodents grew to become glucose intolerant too, showing the modification in gut bacteria was mediating the negative health results of the substitute sweeteners. But rodents are rodents and humans are humans. When the story stopped there, maybe we’re able to shrug from the results and play ignorant, enjoying our Splenda within our morning coffee guilt free. They next examined whether there is a connection between artificial sweetener intake and illness in humans. Affirmed, a greater consumption of sugar substitutes was connected having a greater weigh-to-hip ratio, greater fasting bloodstream sugar, and greater HbA1c.
To demonstrate the causative aftereffect of the substitute sweeteners in humans, they gave 7 healthy individuals who didn’t normally consume sugar substitutes, foods that contains sugar substitutes for 7 days. In only 7 days, 4 from the 7 people developed glucose intolerance (c). In addition to this, once the microbiomes from all of these everyone was transferred into rodents without microbiomes, individuals rodents also grew to become glucose intolerant (g).
Sports drinks could be advantageous for athletes and anybody taking part in prolonged, intense workouts
A potential study on the journal Weight problems checked out the association between sport drink consumption & putting on weight in over 7,500 children and teenagers and noted that individuals who regularly drank sports drinks considered considerably greater than their peers
https://world wide web.ncbi.nlm.nih.gov/pmc/articles/PMC4180814/
When fructose is metabolized, it becomes free essential fatty acids (FFAs) and triglycerides, which gets stored as fat
Fructose converts to activated glycerol (g-3-p), which is often used to show FFAs into triglycerides – The greater g-3-p you’ve, the greater fat you store
Nicholas Norwitz – Oxford PhD Investigator and Harvard Mediterranean Student:
https://world wide web.dpag.ox.ac.united kingdom/team/nicholas-norwitz